USA Flag An official website of the United States government
Official websites use .mil
A .mil website belongs to an official U.S. Department of Defense organization.
Secure .mil websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .mil website. Share sensitive information only on official, secure websites.
 

Technologies Available for Licensing

For Licensing Opportunities, please contact the ORTA at USArmy.Detrick.MEDCOM-USAMRMC.List.ORTA@health.mil



ENHANCED SUBSTRATES FOR THE PROTEASE ACTIVITY OF SEROTYPE A BOTULINUM NEUROTOXIN

Substrates of botulinum toxin serotype A (BoNT A), kits comprising the substrates, and methods of using the substrates are disclosed. BoNT A cleaves SNAP-25 and the substrates that are based upon a portion of SNAP-25. Various amino acid modifications to the sequence of the peptide based on SNAP-25 are performed. Fluorescence labels that act as donors and acceptors may be added to the substrate to aid in the study of BoNT A.


Docket:RIID 2009-40

Publication/Issued No.:WO 2011/047241

Publication/Issue Date:2011-04-21

Categories: Method

More Detail:Visit WIPO.INTExternal link

Lab:RIID

Inventor(s):SCHMIDT, J.; STAFFORD, R.


For Licensing Opportunities, please contact the ORTA at USArmy.Detrick.MEDCOM-USAMRMC.List.ORTA@health.mil
 

Page last modified: 16 Jun 2025

This Web site provides an introduction to the Office of Research and Technology Applications (ORTA) and contains official Government information.

Its use is intended for members of the general public, news media and Military Health System beneficiaries.

Please address questions or concerns about this Web site to the USAMRDC Public Affairs Office at:
USArmy.Detrick.MEDCOM-USAMRMC.List.ORTA@health.mil or by telephone at (301)619-2736.