Technologies Available for Licensing
THERAPEUTIC COMPOSITIONS FOR NEUTRALIZING TYPE I INTERFERONS, AND METHODS OF USE
The inventions describe here cover therapeutic compositions, and methods of use, for neutralizing Type I interferons in a mammal. The compositions contain a soluble Orthopoxvirus IFN-binding protein that is modified to remove the cell-binding region, and that specifically binds to Type I IFNs, and a pharmaceutically acceptable carrier or excipient. Another variation of the invention entails a novel IFN-binding protein that is modified to remove the cell-binding region and the signal sequence.
Docket:RIID 10-17
Publication/Issued No.:9,861,681
Publication/Issue Date:2018-01-09
Categories: Method
More Detail:Visit USPTO.GOV
Lab:RIID
Inventor(s):GOLDEN, ET AL