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DETOXIFIED ENDOTOXIN IMMUNOGENIC COMPOSTITIONS AND USES THEREOF
The present invention provides an immunogenic composition of a lipopolysaccharide vaccine and a non-alum adjuvant. The immunogenic composition may be detoxified J5 core lipopolysaccharide of Escherichia coli non-covalently complexed with group B meningococcal outermembrane protein. Also provided are methods for preventing an infection caused by a Gram-negative bacteria in an individual via administering the immunogenic compositions to the individual.
Docket:WRAIR 05-38
Publication/Issued No.:9,616,116
Publication/Issue Date:2017-04-11
Categories: Vaccine
More Detail:Visit USPTO.GOV
Lab:WRAIR
Inventor(s):CROSS, ET AL