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FUSION PROTEIN COMPRISING THE EXTRACELLULAR DOMAIN OF A FILOVIRUS GLYCOPROTEIN FUSED TO AN IMMUNOGLOBULIN HEAVY CHAIN CONSTANT REGION
This invention provides fusion proteins comprising a Filovirus glycoprotein segment and an immunoglobulin polypeptide segment. The fusion proteins are useful in immunogenic compositions to protect against infections by Filoviruses, such as Ebola virus, in both humans and non-human animals. The fusion proteins are also useful in diagnostic assays to detect Filovirus infections.
Docket:RIID 12-08
Publication/Issued No.:9,347,951
Publication/Issue Date:2016-05-24
Categories: Assay
More Detail:Visit USPTO.GOV
Lab:RIID
Inventor(s):KAPLAN, ET AL