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SIN NOMBRE VIRUS FULL-LENGTH M SEGMENT-BASED DNA VACCINES
The invention contemplates a new synthetic, codon-optimized Sin Nombre virus (SNV) full-length M gene open reading frame (ORF) that encodes a unique consensus amino acid sequence. The SNV ORF was cloned into a plasmid to form the first stable recombinant SNV full-length M gene that elicits neutralizing antibodies. The gene can be engineered into a vaccine system, and is useful to protect mammals against infection with Sin Nombre virus.
Docket:RIID 09-38
Publication/Issued No.:9,315,826
Publication/Issue Date:2016-04-19
Categories: Vaccine
More Detail:Visit USPTO.GOV
Lab:RIID
Inventor(s):HOOPER, ET AL