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ANTIBODIES WITH SIMULTANEOUS SUBSITE SPECIFICITIES TO PROTEIN AND LIPID EPITOPES

Antibodies and method of making antibodies, either monoclonal or polyclonal wherein said antibodies have dual or multi-specific binding capacity to more than one type of antigenic epitope. The antibodies have simultaneous or independent recognition subsites to each of the epitopes. Antigenic epitopes include lipids, peptides, proteins, amino acid sequences, sugars and carbohydrates. Monoclonal antibodies and a method of making monoclonal antibodies of the invention include monoclonal antibodies that are broadly neutralizing to HIV-1 or other envelop viruses wherein the monoclonal antibody has subsites that simultaneously recognize protein and lipid epitopes from the virus.


Docket:WRAIR 05-33

Publication/Issued No.:9,119,828

Publication/Issue Date:2015-09-01

Categories: Antibody Technologies,Vaccine

More Detail:Visit USPTO.GOVExternal link

Lab:WRAIR

Inventor(s):ALVING, CARL

For Licensing Opportunities, please contact the ORTA at USArmy.Detrick.MEDCOM-USAMRMC.List.ORTA@health.mil
 
 

Last Modified Date: 25 Jul 2023

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