USA Flag An official website of the United States government
Official websites use .mil
A .mil website belongs to an official U.S. Department of Defense organization.
Secure .mil websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .mil website. Share sensitive information only on official, secure websites.
 

Technologies Available for Licensing

For Licensing Opportunities, please contact the ORTA at USArmy.Detrick.MEDCOM-USAMRMC.List.ORTA@health.mil



PLASMODIUM FALCIPARUM CIRCUMSPOROZITE VACCINE GENE OPTIMIZATION FOR SOLUBLE PROTEIN EXPRESSION

The present invention provides novel nucleotide sequence and other constructs used for expression of novel recombinant P. falciparum circumsporozoite proteins in bacterial cells such as E. coli. Processes are provided for producing a soluble recombinant P. falciparum CSP from E. coli. Methods to produce a human-grade, highly immunogenic anti-malaria vaccine based on CSP are shown. The novel recombinant P. falciparum circumsporozoite protein by itself or in combination with other malaria antigens or adjuvants can form the basis of an effective malaria vaccine.


Docket:WRAIR 10-28

Publication/Issued No.:9,115,205

Publication/Issue Date:2015-08-25

Categories: Method,Vaccine

More Detail:Visit USPTO.GOVExternal link

Lab:WRAIR

Inventor(s):DUTTA


For Licensing Opportunities, please contact the ORTA at USArmy.Detrick.MEDCOM-USAMRMC.List.ORTA@health.mil
 

Page last modified: 16 Jun 2025

This Web site provides an introduction to the Office of Research and Technology Applications (ORTA) and contains official Government information.

Its use is intended for members of the general public, news media and Military Health System beneficiaries.

Please address questions or concerns about this Web site to the USAMRDC Public Affairs Office at:
USArmy.Detrick.MEDCOM-USAMRMC.List.ORTA@health.mil or by telephone at (301)619-2736.