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COMPOSITIONS AND METHODS FOR SILENCING GENES INVOLVED IN HEMORRHAGIC FEVER
The present invention provides compositions comprising therapeutic nucleic acids such as interfering RNA (e.g., dsRNA such as siRNA) that target Lassa virus (LASV) or tissue factor (TF) gene expression, lipid particles comprising one or more (e.g., a cocktail) of the therapeutic nucleic acids, methods of making the lipid particles, and methods of delivering and/or administering the lipid particles (e.g., for treating hemorraghic fever).
Docket:RIID 2012-01
Publication/Issued No.:8,455,455
Publication/Issue Date:2013-06-04
Categories: Vaccine
More Detail:Visit USPTO.GOV
Lab:RIID
Inventor(s):ROBBINS, ET AL