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The present invention relates to genetically attenuated superantigen toxin vaccines altered such that superantigen attributes are absent, however the superantigen is effectively recognized and an appropriate immune response is produced. The attenuated superantigen toxins are shown to protect animals against challenge with wild type toxin. Methods of producing and using the altered superantigen toxins are described.

Docket:RIID 96-14D

Publication/Issued No.:7,750,132

Publication/Issue Date:2010-07-06

Categories: Vaccine

More Detail:Visit USPTO.GOVExternal link


Inventor(s):ULRICH, R.

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Last Modified Date: 25 Jul 2023

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