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ALTERED SUPERANTIGEN TOXINS
The present invention relates to genetically attenuated superantigen toxin vaccines altered such that superantigen attributes are absent, however the superantigen is effectively recognized and an appropriate immune response is produced. The attenuated superantigen toxins are shown to protect animals against challenge with wild type toxin. Methods of producing and using the altered superantigen toxins are described.
Docket:RIID 96-14D
Publication/Issued No.:7,750,132
Publication/Issue Date:2010-07-06
Categories: Vaccine
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Lab:RIID
Inventor(s):ULRICH, R.