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A vaccine delivered by transcutaneous immunization provides an effective treatment against infections by pathogens such as, for example, enterotoxigenic Escherichia coli (ETEC) and/or for symptoms of diarrheal disease caused thereby. For example, one, two, three, four, five or more antigens derived from ETEC and capable of inducing an antigen-specific immune response (e.g., toxins, colonization or virulence factors) and one or more optional adjuvant (e.g., whole bacterial ADP-ribosylating exotoxins, B subunits or toxoids thereof, detoxified mutants and derivatives thereof) are used to manufacture vaccines or to induce systemic and/or mucosal immunity.

Docket:WRAIR 99-63B

Publication/Issued No.:7,527,802

Publication/Issue Date:2009-05-05

Categories: Vaccine

More Detail:Visit USPTO.GOVExternal link


Inventor(s):GLENN, G.; CASSELS, F.

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Last Modified Date: 25 Jul 2023

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