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RECOMBINANT P. FALCIPARUM MEROZOITE PROTEIN-1.SUB.42 VACCINE
In this application is described the expression and purification of a recombinant Plasmodium falciparum (FVO) MSP-1.sub.42. The method of the present invention produces a highly purified protein that retains folding and disulfide bridging of the native molecule. The recombinant MSP-1.sub.42 is useful as a diagnostic reagent, for use in antibody production, and as a vaccine.
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Inventor(s):ANGOV, E.; DARKO, C.; LYON, J.; COHEN, J.