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BURST –FREE SUSTAINED RELEASE POLY-(LACTIDE/GLYCOLIDE) MICROSPHERES

Novel burst-free, sustained release biocompatible and biodegrable microcapsules which can be programmed to release their active core for variable durations ranging from 1 100 days in an aqueous physiological environment. The microcapsules are comprised of a core of polypeptide or other biologically active agent encapsulated in a matrix of poly(lactide/glycolide) copolymer as a blend of uncapped (free carboxyl end group) and end-capped forms ranging in ratios from 100/0 to 1/99.


Docket:WRAIR 96-M10

Publication/Issued No.:7,033,608

Publication/Issue Date:2006-04-15

Categories: Treatment

More Detail:Visit USPTO.GOVExternal link

Lab:WRAIR

Inventor(s):JEVANTHI, R.; VAN HAMMONT, J.; FRIDEN, P.; REID, R.; ROBERTS, D.; MCQUEEN, C.; SETTERSTROM, J.

For Licensing Opportunities, please contact the ORTA at USArmy.Detrick.MEDCOM-USAMRMC.List.ORTA@health.mil
 
 

Last Modified Date: 25 Jul 2023

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