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VACCINE AGAINST GRAM-NEGATIVE BACTERIAL INFECTIONS

A vaccine, effective in inducing the production of antibodies with which to immunize a second subject passively against infection by Gram-negative bacteria and LPS-mediated pathology, comprises a non-covalent polyvalent complex formed between purified, detoxified LPS derived from E. coli and purified outer membrane protein derived from N. meningitidis. The same vaccine will also actively immunize a host subject against Gram-negative bacterial infections and LPS-mediated pathology. Meningococcal infections are included among those Gram-negative bacterial infections protected against by the vaccine.


Docket:WRAIR 92-17

Publication/Issued No.:7,025,963

Publication/Issue Date:2006-04-11

Categories: Vaccine

More Detail:Visit USPTO.GOVExternal link

Lab:WRAIR

Inventor(s):BHATTACHARJEE, A.; CROSS, A.; SADOFF, J.; ZOLLINGER, W.


For Licensing Opportunities, please contact the ORTA at USArmy.Detrick.MEDCOM-USAMRMC.List.ORTA@health.mil
 

Last Modified Date: 25 Jul 2023

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