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A recombinant protein encompassing the complete envelope glycoprotein and a portion of the carboxy-terminus of the membrane/premembrane protein of dengue 2 virus was expressed in baculovirus as a protein particle. The recombinant protein particle was purified and found to provide protection against lethal challenge with dengue 2 virus in mice.

Docket:WRAIR 95-15

Publication/Issued No.:6,514,501

Publication/Issue Date:2003-02-04

Categories: Vaccine

More Detail:Visit USPTO.GOVExternal link


Inventor(s):KELLY, E.; KING, A.

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Last Modified Date: 25 Jul 2023

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