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IMMOBILIZED ENZYMES BIOSENSORS FOR CHEMICAL TOXINS
Methods, compositions and materials useful in the detection of organophosphorous and organosulfur compounds are disclosed. In particular, biosensors wherein a porous or a non-porous support having an enzyme immobilized upon or within are disclosed. The biosensors exhibit enzymatic stability at extreme temperatures and/or denaturing conditions, and similar kinetic characteristics of the soluble form of the enzymes utilized. The enzyme does not leach from the porous or non-porous support and the material retains enzymatic activity after prolonged storage. Differential biosensors are also disclosed.
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Inventor(s):GORDON, R.; DOCTOR, B.; SAXENA, A.; FEASTER, S.; MAXWELL, D.; ROSS, M.; LENZ, D.; LEJEUNE, K.; RUSSELL, A.