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INACTIVATED DENGUE VIRUS VACCINE
An inactivated dengue virus vaccine to immunize and protect humans against dengue fever is described. The vaccine is based on dengue viruses which have been propagated to high titers in suitable cells, purified and inactivated under conditions which destroy infectivity but preserve immunogenicity, a high level of which is demonstrated in animal models.
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Inventor(s):PUTNAK, J.; ECKELS, K.; DUBOIS, D.