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ENDOTHELIAL-MONOCYTE ACTIVATING POLYPEPTIDE II, A BIOMARKER FOR USE IN DIAGNOSIS OF BRAIN INJURY
A diagnostic tool and method of diagnosing brain injury and brain injury type (traumatic vs. ischemic) by detecting the level of expression of endothelial monocyte-activating polypeptide II (EMAP-II) and comparing to a control. An increase of EMAP-II indicates the presence of traumatic brain injury and a decrease of EMAP-II indicates the presence of ischemic brain injury. Detection of EMAP-II can be done in brain tissue, biofluids such as cerebrospinal fluid or blood (including plasma and serum)
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Inventor(s):DAVE, J.; YAO, C.; WILLIAMS, A.; MAY, XI-CHUN; TORTELLA, F.; WANG, KA-WANG; HAYES, R.