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Described are a therapeutic monoclonal antibody specific for the Type Six Secretion System (T6SS) needle protein of Acinetobacter baumannii (A. baumannii) and methods of use. Specifically, the antibody specifically binds to hemolysin co-regulated protein (Hep). Further disclosed are methods of using an anti-Hep antibody for detecting A. baumannii in a sample as well as a mutant A. baumannii strain comprising a deletion or mutation in its genome such that said deletion or mutation interrupts the proper translation of its hep protein.

Docket:WRAIR 14-27-US02

Publication/Issued No.:10,961,298

Publication/Issue Date:2021-03-30

Categories: Antibody Technologies

More Detail:Visit USPTO.GOVExternal link


Inventor(s):ZURAWSKI, D.

For Licensing Opportunities, please contact the ORTA at

Last Modified Date: 25 Jul 2023

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