https://technologytransfer.health.mil/index.cfm/available_technologies List of issued/pending patents available for licensing. For more information, contact us at usarmy.detrick.medcom-usamrmc.list.orta@health.mil Thu, 16 Apr 2026 04:06:03 GMT https://technologytransfer.health.mil/index.cfm/available_technologies&item=81368051 [81368051] by Patricia M. Legler, Arthur M. Friedlander, Jaimee R. Compton (RIID/Therapeutic) Fri, 22 Sep 2023 00:00:00 GMT https://technologytransfer.health.mil/index.cfm/available_technologies&item=81368051 [81368051] by Patricia M. Legler, Arthur M. Friedlander, Jaimee R. Compton (RIID/Treatment) Fri, 22 Sep 2023 00:00:00 GMT https://technologytransfer.health.mil/index.cfm/available_technologies&item=11%2C253%2C347 A system for conducting inhalation studies includes an inhalation exposure chamber and an aerosol delivery line connected to the inhalation exposure chamber. The aerosol delivery line is configured to produce a bi-directional and symmetrical presentation of aerosol to the inhalation exposure chamber. A laminar flow element is configured to create an ante-chamber where complete and turbulent mixing of the aerosol occurs. A radial exhaust and the laminar flow element enable laminar flow of the aerosol through the inhalation exposure chamber. [11,253,347] by Haupt, B.; Staymates, M.; Bowen, L.; Bailey, M.; Anderson, J. (RIID/Device) Tue, 22 Feb 2022 00:00:00 GMT https://technologytransfer.health.mil/index.cfm/available_technologies&item=11%2C246%2C729 Barrier coatings with efficacy against oxygen and nuisance substances are described that comprise lower molecular weight PVOH and EVOH co-polymers, when coated on flexible substrates. Coating formulations comprising these co-polymers advantageously tolerate moderate to higher proportions of organic solvents in aqueous blends, and thus produce faster drying coating formulations. [11,246,729] by Blanck, R. (BAMC/Design) Tue, 15 Feb 2022 00:00:00 GMT https://technologytransfer.health.mil/index.cfm/available_technologies&item=11%2C246%2C729 Barrier coatings with efficacy against oxygen and nuisance substances are described that comprise lower molecular weight PVOH and EVOH co-polymers, when coated on flexible substrates. Coating formulations comprising these co-polymers advantageously tolerate moderate to higher proportions of organic solvents in aqueous blends, and thus produce faster drying coating formulations. [11,246,729] by Blanck, R. (BAMC/Device) Tue, 15 Feb 2022 00:00:00 GMT https://technologytransfer.health.mil/index.cfm/available_technologies&item=11%2C241%2C194 A system, method and apparatus is disclosed, comprising a biomathetical model for optimizing cognitive performance in the face of sleep deprivation that integrates novel and nonobvious biomathematical models for quantifying performance impairment for both chronic sleep restriction and total sleep deprivation; the dose-dependent effects of caffeine on human vigilance; and the pheonotypical response of a particular user to caffeine dosing, chronic sleep restriction and total sleep deprivation in user-friendly software application which itself may be part of a networked system. [11,241,194] by Reifman, J.; Khitrov, M.; Liu, J; Wesensten, N.; Balkin, T.; Ramakrishnan, S. (TATRC/Method) Tue, 08 Feb 2022 00:00:00 GMT https://technologytransfer.health.mil/index.cfm/available_technologies&item=11%2C241%2C194 A system, method and apparatus is disclosed, comprising a biomathetical model for optimizing cognitive performance in the face of sleep deprivation that integrates novel and nonobvious biomathematical models for quantifying performance impairment for both chronic sleep restriction and total sleep deprivation; the dose-dependent effects of caffeine on human vigilance; and the pheonotypical response of a particular user to caffeine dosing, chronic sleep restriction and total sleep deprivation in user-friendly software application which itself may be part of a networked system. [11,241,194] by Reifman, J.; Khitrov, M.; Liu, J; Wesensten, N.; Balkin, T.; Ramakrishnan, S. (TATRC/System) Tue, 08 Feb 2022 00:00:00 GMT https://technologytransfer.health.mil/index.cfm/available_technologies&item=11%2C224%2C626 The subject matter of the instant invention relates to methods of enhancing harvesting of phages against a targeted host bacteria, as well as methods of identifying phages likely to have an enhanced propensity to infect and kill an infectious pathogenic bacteria in vivo, from samples comprising phages. The invention also relates to phage libraries, pharmaceutical compositions, methods of treatment, and phage-based diagnostic methods and methods of detecting bacteria related thereto. [11,224,626] by Regeimbal, J.; Tyner, S. (WRAIR/Method) Tue, 18 Jan 2022 00:00:00 GMT https://technologytransfer.health.mil/index.cfm/available_technologies&item=81362832 [81362832] by Patricia M. Legler, Arthur M. Friedlander, Jaimee R. Compton (RIID/Therapeutic) Tue, 18 Jan 2022 00:00:00 GMT https://technologytransfer.health.mil/index.cfm/available_technologies&item=81362832 [81362832] by Patricia M. Legler, Arthur M. Friedlander, Jaimee R. Compton (RIID/Treatment) Tue, 18 Jan 2022 00:00:00 GMT https://technologytransfer.health.mil/index.cfm/available_technologies&item=11%2C155%2C834 An assay for detecting, measuring, or monitoring the activity or concentration of at least two proteins that have similar or overlapping properties is disclosed. The assay comprises first determining the sensitivity coefficients of the substrates for each of the proteins in which the concentrations are to be determined. This method may be used for detecting, measuring, or monitoring the activity and concentration of AChE, BChE, or both in a test sample which test sample may be whole and unprocessed blood or tissue. Also disclosed are methods of using the assay to detect a subject's exposure to an agent which affects cholinesterase, determine the efficacy or progress of a treatment, determine the amount of protection provided against exposure to an agent which affects cholinesterase, or both, screen a subject for having a drug sensitivity or a particular disease, detect a change in red blood cell count of a subject, determine whether a candidate compound affects cholinesterase. Also disclosed are devices and kits for detecting, measuring, or monitoring the activities and concentrations of AChE, BChE, or both. [11,155,834] by Hooper, J. (RIID/Vaccine) Tue, 26 Oct 2021 00:00:00 GMT https://technologytransfer.health.mil/index.cfm/available_technologies&item=11%2C123%2C042 An embodiment of the invention provides a method to measure fluid within a body cavity where data is received with an interface (210), the data being received from an ultrasound transducer. A three-dimensional sonographic image is generated with an image generator (220) connected to the interface (210), the three-dimensional sonographic image being generated from the data from the ultrasound transducer. The body cavity is identified in the three-dimensional sonographic image with an image processor (230) connected to the image generator (220); and, an area of fluid in the body cavity in the three-dimensional sonographic image is identified with the image processor (230). The volume of the area of fluid is calculated using the three-dimensional sonographic image and a stacked crescents process, a spherical fill process, a convex hull process, and/or a triangulation process. [11,123,042] by Gusman, (Unknown) (ISR/Device) Tue, 21 Sep 2021 00:00:00 GMT https://technologytransfer.health.mil/index.cfm/available_technologies&item=11%2C123%2C042 An embodiment of the invention provides a method to measure fluid within a body cavity where data is received with an interface (210), the data being received from an ultrasound transducer. A three-dimensional sonographic image is generated with an image generator (220) connected to the interface (210), the three-dimensional sonographic image being generated from the data from the ultrasound transducer. The body cavity is identified in the three-dimensional sonographic image with an image processor (230) connected to the image generator (220); and, an area of fluid in the body cavity in the three-dimensional sonographic image is identified with the image processor (230). The volume of the area of fluid is calculated using the three-dimensional sonographic image and a stacked crescents process, a spherical fill process, a convex hull process, and/or a triangulation process. [11,123,042] by Gusman, (Unknown) (ISR/System) Tue, 21 Sep 2021 00:00:00 GMT https://technologytransfer.health.mil/index.cfm/available_technologies&item=11%2C084%2C046 An embodiment of the invention provides an aerosol concentrating apparatus for use with an aerosol aging drum, where the aerosol concentrating apparatus includes an outer housing, an aerosol inlet tube connected to the outer housing, and an extraction tube connected to the outer housing. An axle connected to the outer housing is axially centered within the outer housing, where the axle is formed from porous material. An inner housing is connected to the axle, such that the axle is axially centered within the inner housing, and such that the inner housing is adapted to spin about the axle within the outer housing to separate aerosol particles by size. Aerosol particles below a first threshold size are forced out of the aerosol concentrating apparatus through the axle; and, aerosol particles between the first threshold size and a second threshold size are suspended within the inner housing. [11,084,046] by Anderson, J.; Bailey, M.; Bowen, L.; Haupt, B. (RIID/Device) Tue, 10 Aug 2021 00:00:00 GMT https://technologytransfer.health.mil/index.cfm/available_technologies&item=11%2C053%2C285 The present invention relates, in general, to human immunodeficiency virus (HIV), and in particular to a vaccine for HIV-1 and to methods of making and using same. [11,053,285] by Kim, J. (WRAIR/Vaccine) Tue, 06 Jul 2021 00:00:00 GMT https://technologytransfer.health.mil/index.cfm/available_technologies&item=11%2C033%2C615 The invention generally relates to a purified inactivated Zika virus (ZIKV), methods for producing the purified inactivated ZIKV, immunogenic compositions and vaccines comprising the purified inactivated ZIKV and methods for the prevention and/or treatment of infection by ZIKV. [11,033,615] by Thomas, S.; Endy, T.; Eckels, K.; Putnak, J. Robert; Jarman, R; De La Barrera, R. (WRAIR/Vaccine) Tue, 15 Jun 2021 00:00:00 GMT https://technologytransfer.health.mil/index.cfm/available_technologies&item=2019203166 [2019203166] by Pletnev, A.; Putnak, J. (WRAIR/Vaccine) Thu, 10 Jun 2021 00:00:00 GMT https://technologytransfer.health.mil/index.cfm/available_technologies&item=11%2C027%2C086 In at least one embodiment, a system includes an inhalation source; a plenum in fluid communication with the inhalation source; at least one challenge plethysmography mask in fluid communication with the plenum, for each challenge plethysmography mask including a mask having a cavity to receive at least a nose of a test animal, a delivery conduit in fluid communication with the plenum and the cavity of the mask, at least one exhaust conduit in fluid communication with the cavity of the mask and the plenum, and a pressure sensor attached to the mask to measure pressure within the cavity of the mask; at least one processor in electrical communication with the at least one pressure sensor, the processor configured to process an outmask put signal of the pressure sensor into respiratory data for each test animal during an exposure study; and an exhaust system in fluid communication with the plenum. [11,027,086] by Bowen, L. (RIID/Device) Tue, 08 Jun 2021 00:00:00 GMT https://technologytransfer.health.mil/index.cfm/available_technologies&item=11%2C027%2C086 In at least one embodiment, a system includes an inhalation source; a plenum in fluid communication with the inhalation source; at least one challenge plethysmography mask in fluid communication with the plenum, for each challenge plethysmography mask including a mask having a cavity to receive at least a nose of a test animal, a delivery conduit in fluid communication with the plenum and the cavity of the mask, at least one exhaust conduit in fluid communication with the cavity of the mask and the plenum, and a pressure sensor attached to the mask to measure pressure within the cavity of the mask; at least one processor in electrical communication with the at least one pressure sensor, the processor configured to process an outmask put signal of the pressure sensor into respiratory data for each test animal during an exposure study; and an exhaust system in fluid communication with the plenum. [11,027,086] by Bowen, L. (RIID/System) Tue, 08 Jun 2021 00:00:00 GMT https://technologytransfer.health.mil/index.cfm/available_technologies&item=11%2C013%2C791 The disclosure generally provides a WRrNYVAC comprising multiple antigens from different stages of a malaria parasite (Plasmodium) life cycle, methods for producing them, immunogenic vaccine formulations comprising WRrNYVAC, such as P. vivax containing formulations (WRPvrNYVAC) and P. falciparum containing formulations (WRPfrNYVAC) and methods for the prevention and/or treatment of malaria infections and poxvirus infections. [11,013,791] by Hauns, K. (WRAIR/Vaccine) Tue, 25 May 2021 00:00:00 GMT